
image caption The plane was en route from Honolulu to Kahului on the island of Maui when it crashed
The aircraft was en route from Honolulu to the island of Maui, but went down in the water soon after taking off from Daniel K Inouye International Airport.
The Coast Guard rescued both pilots from the sea early on Friday morning.
One was found clinging to the plane’s tail and airlifted to safety, Reuters news agency reports.
According to officials from the state’s transport department, quoted by local outlet Hawaii News Now (HNN), he was airlifted to Queen’s Medical Center and taken to intensive care in critical condition.
Rescuers brought the other pilot to shore by boat, HNN said. He is reportedly in a serious condition with a head injury.
A Boeing statement reported by US media said they were in contact with authorities about the incident and are “closely monitoring the situation”.
Flight tracking website Flightradar24 tweeted that it was a 737-200 cargo aeroplane operated for the carrier Transair since 2014. It was built in 1975 and first delivered to Pacific Western Airlines.
Transair Flight 810 left Honolulu bound for Kahului at 01:33 local time (11:33 GMT), Flightradar 24 said, but turned back quickly afterwards, and crashed into the water after just minutes in the air.
According to its website, Transair has been in business since 1982 and is one of Hawaii’s biggest air cargo operators. It has a fleet of five Boeing 737s, it said.
The 737 Max was cleared to fly again by US regulators in 2020, but it recently came under further scrutiny.